Background:Cancer survivors are increasing globally, including Korea. This might be due to earlier detection of cancer, more improved treatment of cancer and nationally increased concern of public health. Recently, higher rate of comorbidities in cancer survivors is reported and chronic kidney disease(CKD) is, one of them, shares risk factors of cancers.
Aim:There is lack of study to reveal that cancer survivors have higher risk of CKD prevalence, therefore we aimed to evaluate the association of cancer survivors and the prevalence risk of CKD using the 2010-2012 Korean National Health and Nutrition Examination Survey (KNHANES).
Methods:11,296 subjects(4,671 in men and 6,625 in women) were included, and divided into two groups by cancer experiences. Multiple variables including age, sex, CKD prevalence, body mass index, daily calorie intake, smoking, alcohol drinking, and physical exercise were compared between two groups.
Results:In men, mean values of body mass index, blood pressure, daily calorie intake, and the percentage of current smokers were lower in cancer survivors. In women, body mass index, daily calorie intake, hight risk drinkers and current smokers were lower, but not significantly different in cancer survivors group. In logistic regression analyses, cancer survivors have the higher prevalence risk for CKD after multiple variables were fully adjusted, which was ORs (95% CIs) of cancer survivors for CKD were 4.13 (1.19 – 15.10) in men and 2.75 (1.21 – 6.21) in women.
Conclusions:Our study demonstrated that there might be association between CKD and cancer survivors in Korean adults. Iidentification of direct or indirect multifactorial factors of the association would bring positive effects on prevention of the disease progression of CKD and cancer and minimizing burden on public health in the furture.