E-poster Presentation 2014 World Cancer Congress

Male breast cancer: Epidemiological study in patients attended in three academic hopistals in São Paulo (#910)

Marcelo Calil 1 , Eliana Araujo 1 , Felipe Cruz 1 , Damila Trufelli 1 , João Carlos Sampaio Góes 1 , Auro del Giglio 1
  1. Instituto Brasileiro de Controle do Câncer, São Paulo, SP, Brazil

INTRODUCTION: Male breast cancer is rare, accounting for approximately 1% of all cases of breast cancer. In 2013, 2240 new cases of breast cancer in men were diagnosed in the United States, with 410 deaths secondary to that disease. The purpose of this study was to describe the epidemiological, and pathological characteristics and treatments used in male patients with invasive breast cancer treated in three oncology referral academic hospitals.

METHODS: This retrospective study assessed data from medical records of male patients with invasive breast cancer diagnosed between February 2003 and April 2013, attended at Hospital Estadual Mário Covas (HESA), Hospital Padre Anchieta (HA) and Instituto Brasileiro de Controle do Câncer (IBCC). Data were subjected to statistical analysis.

RESULTS: In 35 cases surveyed, the median age was 65 years. Most patients presented stage II disease at diagnosis. The most prevalent histological type was invasive ductal carcinoma, as well as hormonal receptor positivity. About 96.8% underwent mastectomy and 69% axillary dissection. Chemotherapy was indicated for 73.5% and endocrine therapy with tamoxifen in 88.5%. Overall survival and progression free survival at 5 years were 78.3% and 66% respectively. The median follow-up of these patients was 20 months.

Conclusions:CONCLUSION: The epidemiological and pathological features, as well as treatment, are similar to literature. The stage II was the most prevalent in our sample, different from those described in the literature.